THINK OF EVOVITE POWDER AS POTENT NUTRITIONAL INSURANCE FOR YOUR FITNESS LIFESTYLE.
Our goal is to bridge health and physique perfection, and we firmly believe EVOVITE POWDER helps to achieve this. EVOVITE POWDER is far beyond a mere high-potency multivitamin. It’s really three supplements in one:
A multivitamin/mineral formula with exceptional ingredient forms
A clinically validated beta-alanine supplement
A technologically superior curcumin supplement
The reality is, many multivitamin formulations use cheap forms of vitamins and minerals, and often times boast to having up to 70 ingredients that are largely not proven to do anything at the levels they contain. Not EVOVITE POWDER. Quality and potency came first. This is why Evogen CEO and master physique coach, Hany “the Pro Creator” Rambod, created this potent formulation. It’s designed to not only support health and fill gaps in your daily nutrition, but to increase performance. If you don’t like pills or want to increase your post workout stack’s potency, EVOVITE POWDER will make a great addition to any protein shake.
SUPERIOR INGREDIENTS FOR SUPERIOR RESULTS
Albion® Certified Chelated Minerals
When it comes to nutrition it’s hard to replace the nutrients found in wholefoods. However, because many farm-raised crops have less and less vitamin and mineral composition, it’s important for active athletes to supplement with key minerals such as zinc, magnesium, potassium, etc. An athlete’s RDA requirements are higher than normal due to their increased activity levels from weightlifting, cardio, and active lifestyles. For these reasons, EVOVITE POWDER uses only the highest quality chelated minerals. These minerals are bound to amino acids to help ensure maximum bioavailability and utilization by the body. The body naturally chelates certain minerals, so chelated minerals help save a few biochemical processes for your body. It makes no sense to supplement with low quality minerals that ultimately don’t get absorbed, and this is why EVOVITE POWDER sets the standard for high quality chelated mineral formulations.
Oftentimes you see pre-workout formulations hyper-loaded with beta-alanine. Unfortunately, research does not support this. What research does support is taking smaller doses of beta-alanine throughout the day, EVERY day. With this in mind, EVOVITE is meant to be taken once a day, with food, and stacked with other products such as EVP XTREME, which also contains beta-alanine. This coupling helps ensure maximum intra-muscular carnosine synthesis due to other cofactors needed to produce carnosine being readily available, such as magnesium, ATP, histidine, etc. Supplementing 1.2 grams of beta-alanine has actually been shown to maintain high carnosine levels in active men after beta-alanine loading. Higher carnosine levels are what cause increases in performance and endurance, so no matter what beta-alanine product you use along with EVOVITE, you can rest assured you’re receiving a clinically validated total of beta-alanine throughout the day in the manner it was intended to be ingested, not just pre-workout a few times per week.
Longvida SD® Curcumin Extract
Curcumin is one of the most exciting general health ingredients on the market, and for good reason. As an antioxidant that passes the blood-brain barrier, curcumin can promote and support brain health by fighting free radicals, which can cause oxidative stress for cells. As an inflammation-control support agent, curcumin helps improve joint comfort and promotes optimal joint health and motion. Curcumin can also assist in maintaining healthy levels of LDL cholesterol while promoting optimal brain, heart, and blood vessel health. Evogen not only utilizes curcumin, but Longvida SD® optimized curcumin. Through cutting-edge technology, this patented form of curcumin can deliver free curcumin into target tissues through the critical bioavailability requirements of permeability, solubility, and stability. Developed in collaboration with elite neuroscientists at UCLA, Longvida® carries a wealth of research behind it. Unlike many other forms of curcumin which have low bioavailability, the form used in EVOVITE is superior, and gets absorbed with ease to support general health and recovery. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. †When combined with a proper exercise and nutrition program. Please consult with your physician before using this or any other dietary supplement product. [block id="evogreens-720x90"] [block id="carnigen-naturals-728x90"]
Life is too short to live without the Evogen : EVOVITE POWDER Orange Mango 30 Serv. Be happy. Be Content. Be Satisfied.
Restores energy levels to improve athletic performance and everyday quality of life!
Ribose is a naturally occurring substance used by every cell in your body to synthesize and rebuild energy. Ribose is the most fundamental building block of adenosine triphosphate (ATP), the primary source of energy for every muscle cell in your body. ATP gives your body the energy it needs to stay healthy, overcome fatigue, and regain the vitality you need to live a normal, active life. That is why ATP is called the energy currency of the cell.
Benefits of supplementing with Ribose
Ribose helps energize your heart and muscles by increasing energy on a cellular level. Aging, strenuous exercise or overexertion, and many metabolic or physiological conditions can drain ATP from your tissue and affect how well your body makes and uses energy. Science has proven that ribose is a necessary ingredient for rebuilding energy in our bodies. So, without ribose we cannot make the energy we need to stay healthy.
Unfortunately, hearts, muscles, and other vital tissues in the body cannot make ribose very quickly, and ribose is not stored in our cells and tissues. That's why supplementing with ribose as directed will help your cells make energy - quickly, safely, and naturally. This means you can feel more energetic, stronger, and healthier every day.
Energy to Power Metabolic Health Wellness:
Like a computer, your body needs energy to keep running. Energy keeps your heart beating, your muscles contracting, and your brain and nervous system carrying the messages that synchronize the functions of life. For the most vital task of making the energy you need, your body produces ribose.
a-D-Ribofuranose (D-ribose, or simply ribose) is a five-carbon monosaccharide that is made in every cell in your body. Ribose stimulates the metabolic pathway used by the body to make a class of compounds called purines and pyrimidines. These compounds are essential for the body's production of many vital constituents, including the genetic material DNA and RNA, and the vital energy compound adenosine triphosphate (ATP). ATP is called the energy currency of the cell because it gives our bodies the power to function, survive, and thrive. ATP is critical to health and a healthy lifestyle, and ribose is the essential component in the making of ATP in the body.
How to use?
As a dietary supplement, take 5 grams twice daily. Take 30-45 minutes before and after exercise or physical activity. Additional doses may be taken during the activity if the duration of exercise is prolonged (several hours).
WARNING:NOT INTENDED FOR USE BY PERSONS UNDER THE AGE OF 18. KEEP OUT OF THE REACH OF CHILDREN. If you are pregnant or breast feeding, consult your health care professional before using this product. People with known medical conditions and/or taking drugs should consult with a licensed physician prior to taking. Ribose will temporarily depress blood sugar several points for an hour after ingestion. This is usually sub-clinical. However, it is recommended Ribose be taken with food, juice or around meal time to avoid potential symptoms of hypoglycemia.
The Nutrabio Ribose Powder 500 grams is a sensational customer favorite, and we hope you like it just as much.
It’s been called the most important meal of the day.
Eating high quality, fast-acting carbohydrates and protein create the conditions for growth after a workout. Core PWO takes the guesswork out of post workout recovery, containing the fast-acting proteins and carbs needed to maximize muscle recovery after weight training.
2 scoops per serving.
28 servings per container.
High carb for maximum recovery.
It has been called the most important meal of the day, “the anabolic window,” and eating for anabolism. Whatever name you give it, the premise remains: post workout (PWO) nutrition is crucial to reaching your fitness and physique goals. Post workout nutrition plays a number of critical anabolic (tissue building) functions, chief among them the maximization of glycogen storage and protein synthesis, while simultaneously minimizing protein breakdown and the excessive release of catabolic (tissue destroying) hormones. Incomplete or insufficient PWO nutrition is like fueling your new Maserati with regular unleaded – you simply don’t do it.
This all raises the question: what is the ideal post workout nutrition? Is it well known, or a secret? Maybe a certain ratio of carbohydrates to protein, or fat to protein; maybe the timing and frequency? In fact, the situation is vastly less complex, more well-known, and easier to implement than most would have you believe.
High quality, fast-acting carbohydrates and protein have been shown time and again to induce the most optimal conditions for growth in clinical studies – and that is precisely what Core has attempted to emulate with Core PWO. Core PWO takes the guesswork out of post workout recovery, containing the fast-acting proteins and carbs (whey isolate, dextrose, Carb10™ and Cluster Dextrin®), along with other anabolic agents (free-form L-Leucine and Velositol®) needed to maximize muscle recovery after weight training. These ingredients quickly replenish muscle glycogen and shuttle much needed amino acids to muscle cells. Whether you are bulking up or slimming down, all of these ingredients are crucial for proper recovery.
Recovery Carb Blend (Dextrose, Carb 10™ and Cluster Dextrin®):
As mentioned above, one of the main goals post workout is to restore muscle glycogen that has been depleted during the workout. The body will even break down muscle tissue for this purpose if an adequate influx of glucose – obtained from the consumption of carbohydrates – is not provided. For this reason, it is vital to include carbohydrates in the post-workout drink.
Thoughopinionvaries, the scientific literature is relatively clear that fast–digesting carbohydrates such as dextrose, Carb 10™, and Cluster Dextrin® create optimal conditions for the post-workout synthesis of both skeletal muscle protein and muscle glycogen. Not only have all three of Core PWO’s carbohydrates sources demonstrated higher rates of post-exercise glycogenesis (glycogen resynthesis) as compared to other carbohydrate sources, they have also been shown to optimize insulin response and blunt cortisol release to a greater degree than other carbohydrate sources.
Dextrosefunctions at such a higher capacity because of molecular structure, given that it is otherwise known as pure glucose – your body’s preferred energy substrate and the necessary component for the synthesis and resynthesis of glycogen. Bypassing the lengthy and metabolically costly process of digestion and breakdown, dextrose can be absorbed directly through the gut into the bloodstream and can cause an insulin response faster than any other carb. Additionally, since dextrose is already in the form the body requires, it can be used immediately for glycogen replenishment.
Carb10™is an entirely different creature, which functions in PWO to round out the insulin response. Created not from maltodextrin or glucose, but rather peas, Carb10™ is a clean and sustained means of providing your body with its nutritional needs in the post workout environment. Carb10™ also possesses low osmolality, a term used to describe the concentration of a solution. In this case, low osmolality means that Carb10’s transit through the stomach and into the intestine’s is both quicker and more efficient than other carbohydrates sources – meaning it delivers nutrients quickly, while still being low glycemicandreducing bloat. Think of it like other carbohydrates causing a traffic jam, while Carb10™ cruises through the carpool lane.
In total, Carb10™ possesses a wide range of benefits. Including:
Minimal blood-sugar and insulin response
Fast gastric-emptying formula reduces bloating
Prebiotic, non-allergenic, non-GMO and gluten-free.
Cluster Dextrin®, the last of PWO’s carb sources, is derived from corn. Though dissimilar in molecular structure and source from Carb10™, it’s similar in terms of its low osmolality leading to expedient stomach clearing and low bloating. Research conducted on top swimmers, swimming in a flowing water pool, confirmed that Cluster Dextrin’s fast gastric emptying contributed to increased endurance (longer swim times). Swimmers provided a sports drink containing Cluster Dextrin had approximately 50% longer swim time than swimmers provided a mixture of water and glucose only.
In combination, the carbohydrates in Core PWO, in their precise serving sizes, interact to form a comprehensive post-workout nutrition strategy:
Dextrose acts quickly to create an immediate supply of glucose and to stimulate post-workout insulin levels.
Due to their molecular structure, Carb-10™ and Cluster Dextrin balance that insulin response.
Together, they all rapidly, and in a sustained fashion, provide your body with a prime environment for the synthesis of both glycogen and skeletal muscle
And most importantly, they do so without the bloat!
Clinical research is clear that carbohydrates of this type, in combination with whey protein isolate, rapidly reverse high levels of cortisol and low levels of insulin that are associated with high intensity exercise. The rapid, but very beneficial, influx of glucose from oral carbohydrate supplementation quickly suppresses cortisol and the negative effect it has on the expression of metabolically critical proteins and growth factors – ensuring that myocytes (muscle cells) function in an ideal environment. In addition, these carbohydrates induce a beneficial insulin response, the effects of which include stimulating glycogen storage, the transport of glucose into muscle cell mitochondria, and an increase in amino acid utilization.
Cold-Processed Microfiltered Non-GMO Whey Protein Isolate:
If the post-workout environment were a jungle, whey protein isolate would be the lion – its king. While it is difficult to overstate the critical role that post-exercise protein consumption plays in both a macro (body composition) and micro (small-scale, physiological changes) context, some ambiguity remains: what is the ideal form, frequency, timing, and amount of protein consumption post-exercise? Luckily for you, Core Nutritionals’ research hounds have crunched the numbers and read the studies for you, and the result is a very precise amount of whey protein isolate included in Core PWO.
In a statement that should not surprise a single athlete or casual weightlifter, intense resistance training has a profound effect on the function and structure of skeletal muscle and muscle proteins. Immediately following an intense bout of resistance exercise, a process known as muscle protein breakdown – with its sidekick, leucine oxidation – begin to literally tear down your skeletal muscle from the inside. While resistance training simultaneously increases a process known as protein synthesis, the fractional synthesis rate (how quickly the protein is synthesized) is often far exceeded by the rate of muscle protein breakdown and leucine oxidation. The result is that, in that absence of mitigating factors such as post-workout nutrition, your body is in a state of negative protein balance – i.e., catabolism.
In order to counteract a negative intramuscular protein balance, a number of things need to occur – mostly, a rapid increase in the availability of amino acids, and the optimization of several metabolically critical hormones (such as insulin). The combination of protein and carbohydrates contained in Core PWO achieves precisely this balance, and research on whey protein and dextrose in combination demonstrates that this combination maximizes the stimulation of muscle protein synthesis and results in even greater muscle anabolism than either alone.
Free Form Leucine:
The branch-chained amino acids leucine, isoleucine, and valine are famous for their role in skeletal muscle protein synthesis and metabolism, and additionally comprise approximately one-third of all skeletal muscle protein. Of the three, leucine is both the most physiologically important with respect to muscle mass, and the most extensively studied. Data on leucine demonstrate this amino acid plays critical roles in stimulating skeletal muscle protein synthesis, and ribosomal biogenesis and assembly (the literal building of muscle tissue), along with playing a lesser role in insulin signaling and gluconeogenic processes. As a result of these diverse roles, leucine has been demonstrated to significantly stimulate skeletal muscle protein synthesis, and attenuate protein degradation, by both insulin-mediated and non-insulin mediated mechanisms.
Leucine’s insulin-mediated effects are largely the result of its activation of the classical insulin receptor substrate (IRS)/phosphatidylinositol (PI) 3-kinase (PI3K)/Akt/mTOR signal transduction pathway. In this pathway, the bonding of a substrate (Insulin activates a compound known as PI3K, which in turn activates, Akt. Once phosphorylated and activated, Akt signals the release of the famous mammalian target of rapmycin (mTOR). mTOR then increases the translation of muscle-cell ribosomal proteins that increase ribosome biogenesis, which is the literal production of proteins. Leucine plays a critical role in all of this, creating the translation initiation factors that are the rate-limiting step in the production of the ribosomes spoken about above. Carbohydrates alone, other essential amino acids, and non-essential amino acids have not been shown to have the stimulatory effects on muscle protein synthesis – leucine alone has, highlighting is primacy as a muscle protein activator. Leucine has additionally been shown to positively regulate protein synthesis independent of insulin. In certain trials where rapamycin and leucine were co-administered, rapamycin showed only partial inhibition of leucine’s effects on muscle protein synthesis. Rapamycin is also a critical component to the PI3K/Akt/mTOR pathway, as the mTOR (mammalian target of rapamycin) suggests. One of rapamycin’s primary functions is to inhibit mTOR. So, if leucine-mediate protein synthesis is only partially blocked by rapamycin, but rapamycin fully inhibits mTOR, this suggests that leucine-mediate protein synthesis is only partially dependent on the PI3K pathway.
Velositol™, a patented complex of amylopectin/chromium, is a fascinating compound – with emerging clinical data to suggest that it is effective in significantly enhancing skeletal muscle protein synthesis when combined with whey protein (vs whey alone).
In a double-blind crossover study, featuring 10 exercise-trained adults, researchers combined Velositol™ with 6g of whey protein to measure what effects, if any, the compound would exert on skeletal muscle protein synthesis. (The control group consumed 6g of whey alone.) After collecting baseline muscle biopsies – to measure phenylalanine, a marker of muscle-building – the subjects performed eight reps of leg extensions. A final muscle biopsy was taken post-workout, to measure the changes in muscle protein synthesis between the study and control group.
The results were significant: the researchers found that muscle protein synthesis had nearly doubled in the Velositol™ group, compared to the control. The researchers hypothesized that the mechanism of action of Velositol is the stimulated uptake of leucine and other amino acids due to an influx of insulin (from the chromium).
While further study is warranted, the existing data on Velositol™ suggests it’s a must-have addition to any recovery matrix.
The Core Nutritionals : PWO Chocolate Brownie Batter 4lb is evocative, to say the least, but that's why you're drawn to it in the first place.
Inventory Last Updated: Aug 03, 2020
Core Nutritionals : ABC
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Core ABC is the athlete’s BCAA.
The most effective, scientifically-established ratio of BCAAs because we know it’s the difference between your first mile and your last. Include clinically-verified servings of beta-alanine, citrulline malate, and glutamine because we know your last rep depends on it.
2 scoops per serving.
50 servings per container.
Comprehensive recovery blend.
Rep by rep. Mile by mile. Breath by breath. Every muscle screams at you with pleas of mercy; every bone aches to its core from the pressure. Yet, you still don’t quit – you push on. By hook, or by crook, you will make it. You will succeed. You will win. You see, you’re an athlete. You are someone defined to your core by the competitive drive to better yourself at all costs. You need neither trophies, nor accolades; neither cheers, nor recognition. You pay the sweat price for every gain marked in your battle-worn ledger, detailing the struggle your body has endured.
You’re an athlete, and so are we. We don’t make Core ABC for everyone, we make it for you and us. We use the most effective, scientifically-established ratio of BCAAs because we know it’s the difference between your first mile and your last. We include clinically-verified servings of beta-alanine, citrulline malate, and glutamine because we know your last rep depends on it. We know this because we know you, and we know ourselves.
Core ABC is the athlete’s BCAA. It was formulated by athletes, for athletes, for the needs only an athlete can understand. If you can’t say the same about your BCAA, then it may be time for a switch.
If one were to think of the body as a construction project, amino acids would be the most basic building materials: raw lumber, mortar, bricks, and so on. While the assembly of these building blocks is of course critically important to the function of the building – and one of the amino acids, leucine, controls its own assembly – the quality and availability of the materials themselves is arguably more important. Not enough concrete? The foundation cracks and the building falls.
Your body is the exact same way. It is comprised of various amino acids, both essential and non-essential, that comprise the cellular basis of each and every cell in your body. When it comes down to skeletal muscle, the three most important are known as the BCAAs – or branch chained amino acids. Comprised of leucine, isoleucine, and valine, these three little amino acids effectively control the rate at which your muscle grows (hypertrophies), its contractile force, its endurance, and so on – to say they are massively important is an understatement. For this reason, they form the basis of any competently-designed supplement protocol.
Collectively, as stated above, the branch-chained amino acids leucine, isoleucine, and valine are famous for their role in skeletal muscle protein synthesis and metabolism, and additionally comprise approximately one-third of all skeletal muscle protein. Of the three, leucine is both the most physiologically important with respect to muscle mass, and the most extensively studied. Data on leucine demonstrate this amino acid plays critical roles in stimulating skeletal muscle protein synthesis, and ribosomal biogenesis and assembly (the literal building of muscle tissue), along with playing a lesser role in insulin signaling and gluconeogenic processes. As a result of these diverse roles, leucine has been demonstrated to significantly stimulate skeletal muscle protein synthesis, and attenuate protein degradation, by both insulin-mediated and non-insulin mediated mechanisms.
Leucine’s insulin-mediated effects are largely the result of its activation of the classical insulin receptor substrate (IRS)/phosphatidylinositol (PI) 3-kinase (PI3K)/Akt/mTOR signal transduction pathway. In this pathway, the bonding of a substrate (glucose) eventually activates a compound known as Akt. Once phosphorylated and activated, Akt signals the release of the famous mammalian target of rapmycin (mTOR). mTOR then increases the translation of muscle-cell ribosomal proteins that increase ribosome biogenesis, which is the literal production of proteins. Leucine has additionally been shown to positively regulate protein synthesis independent of insulin. In certain trials where rapamycin and leucine were co-administered, rapamycin showed only partial inhibition of leucine’s effects on muscle protein synthesis.
In more practical terms, there is a significant body of evidence demonstrating the positive effect of BCAA’s on athletic performance. Extensive studies in exercise-trained populations reveal that, collectively, BCAA’s may:
Reduce total muscle soreness after intense resistance training, and/or further delay its onset.
Decrease muscle recovery time between bouts of intense resistance exercise training.
Increase lean body mass when used daily, in conjunction with diet and exercise.
While products with larger BCAA ratios (ratio of leucine, to isoleucine, to valine) have recently flooded the market, Core Nutritionals has remained with the gold standard of 2:1:1. This decision is made in recognition of the fact that, for all its potential benefits, there is no evidence demonstrating a realized effect of a larger BCAA ratio – and in fact, all the benefits mentioned above derive from evidence using the gold standard 2:1:1 ratio.
Carnosine is a bit of an odd duck: we know that it is crucial for muscle function, and that dietary sources of caronsine are essential, but we don’t knowpreciselyhow its working. Moreover, for decades, we had no idea how to increase intramuscular concentrations, as exogenous carnosine sources degraded in the body so fast as to be effectively useless.
Enter beta-alanine. Simply a different iteration of one of the amino acids that comprises carnosine itself (alanine), beta-alanine has proven to be the most effective means of significantly increasing intramuscular concentrations of carnosine – and therefore of promoting all of carnosine’s various beneficial effects on muscle performance. If that weren’t enough, beta-alanine has also demonstrated beneficial physiological effects independent of its parent compound. In order to understand why, though, we need to first understand some of the basic behind carnosine itself.
Carnosine, a cytoplasmic dipeptide synthesized from the precursors L-histidine and l-alanine, is present in high concentrations in skeletal muscle and plays a pivotal role as a, “chemical buffer” in myocytes (muscle cells). It has long been known that carnosine concentrations are highest in glycolytic, rather than oxidative muscle fibers (roughly speaking, explosive vs., endurance muscle fibers, respectively), and thus long hypothesized that this amino acid is required for sustained performance during supramaximal exercise. Recent research demonstrates that carnosine exerts its physiological effects in long hypoxic (low oxygen) drives by functioning as a high-capacity pH buffer in skeletal muscle, preventing the pH ratio of plasma from dropping too low – and therefore preventing crucial pH-dependent processes such as protein synthesis from being inhibited by acidosis.
Despite its critical role in skeletal muscle anaerobic performance, intramyocellular synthesis of carnosine is rate-limited by the availability of l-alanine. Unfortunately, the majority of literature demonstrates that attempting to increase intramuscular levels of carnosine via either direct carnosine or alanine supplementation is largely ineffective due to carnosine/alanine pharmacokinetics. Enter beta-alanine. Research with beta-alanine demonstrates consistent and dose-dependent increases to intramuscular carnosine concentrations with beta-alanine supplementation, with certain studies showing an increase of 40-60% with chronic administration. These same literature reveal a synergistic effect of exercise on beta-alanine supplementation, whereby the muscle adaptive changes associated with resistance training promote further intramuscular carnosine production in response to beta-alanine supplementation.
In simpler language, this essentially means that beta-alanine is a dietary supplement that promotes its own effects in combination with exercise. As you exercise, you simultaneously intensify beta-alanine’s physiological actions – both directly, as well as in the production of intramuscular carnosine. Once ingested, beta-alanine’s exercise-specific beneficial activity is well-established. Elevation of intramuscular caronsine content via beta-alanine supplementation has been show to improve performance in the following ways:
Both acute and chronic increases in total work capacity, measured by total volume during exercise sessions.
Highly significant increases to TTE (total time to exhaustion), one of the most accurate and comprehensive measures of endurance. In various trials, beta-alanine supplementation has been shown to increase TTE by upwards of 20%.
Increases to total muscle power output in both acute and chronic trials, suggesting that beta-alanine’s most significant benefit is to those engaging in power-dependent resistance training.
In total, a significant body of research exists to suggest that beta-alanine may significantly increase muscle power output, strength, training volume and output, overall performance in hypoxic (oxygen-deprived) conditions and peak VO2 max (oxygen holding capacity).
These myriad benefits make beta-alanine both one of the most-studied, and most well-rounded dietary supplements. Beta-alanine not only has direct, actionable physiological effects, but also promotes critical muscle physiologic adaptations that promote its own effects.
Citrulline is a non-essential, non-protein amino acid heavily involved in the urea cycle. Citrulline is also a critical source of endogenous (natural) arginine, as it is rapidly and efficiently converted to arginine in the vascular endothelium and other tissues. Arginine, in turn, is used as the substrate by NOS (nitric oxide synthase) to produce NO, more commonly known as nitric oxide.
Citrulline’s benefits have been shown to be greater than its parent compound. While arginine undergoes direct hepatic (liver) metabolism through the enzyme arginase, citrulline bypasses hepatic metabolism entirely and it is delivered straight to the bloodstream. The result is that gut absorption and plasma (blood) bioavailability studies comparing citrulline and arginine have shown two things. First, that citrulline is less readily destroyed and has greater absorption than arginine. Second, that citrulline supplementation increases arginine levels more effectively than arginine supplementation itself.
This translates to promising results. For example, animal studies show a significant increase in anaerobic performance at a 250mg/kg/day serving of citrulline, while studies in humans implicate citrulline in both aerobic and anaerobic performance increases. As a critical part of the urea cycle, citrulline’s performance benefits are thought to be a result of its role in ammonia clearance. Citrulline is implicated in reducing the oxygen cost of muscle processes, along with increasing the rate of post-exercise ATP and phosphocreatine replenishment. As ATP and phosphocreatine are the body’s ‘exercise fuel,’ this may result in citrulline delaying time to exhaustion in aerobic and anaerobic exercise.
Prior to discussing the physiological effects of glutamine – and more specifically, whether or not it poses any tangible benefits to the proliferation of skeletal muscle tissue – we need to discuss its place in supplementation, in general. Glutamine is perhaps the most lamented of all the amino acids, regularly denigrated to the point that it’s a joke to many athletes. This is largely a problem of perception: glutamine is not, specifically speaking, an anabolic amino acid, and therefore is of little use as it pertains to, “building tissue.” But, “building tissue” is not the only purpose a supplement may have, and the corollary, preserving tissue (or anti-catabolism) is arguably as important. It is in this capacity that glutamine shines, and for this reason it is included in Core ABC.
The literature in this context is encouraging. Various studies demonstrate that glutamine supplementation may suppress or inhibit the action of enzymes known as proteases, responsible for the hydrolytic breakdown of protein and amino acids into smaller compounds. These studies show both site-specific and whole-body reductions in this process known as, “proteolysis” in the later stages of skeletal muscle recovery. While encouraging, these data are perhaps not as promising as glutamine’s more indirect effects on the catabolic process – namely its effect on glucose metabolism. In both in vitro and in vivo trials, glutamine has shown the ability to promote the synthesis and storage of glycogen (glycogenesis), both in concert with an independent of carbohydrate ingestion.
These effects are most pronounced in physiologic situations where carbohydrate metabolism reliant on insulin signaling are compromised – such as the chronic caloric deficits present in a dieting situation. In this context, glutamine may function as a critical addition, potentiating the body’s glycogen synthesis and storage response; maximizing the limited amount of carbohydrates a dieter may be ingesting.
1: Valerio, A., D’antona, G., et al. BCAAs, Mitochondrial Biogenesis, and Healthspan: An Evolutionary Perspective. Aging. May 2011. 3(5), 464-470.
2: Bajotto, G., Sato, Y., et al. Effect of BCAA Supplementation During Unloading on Regulatory Components of Protein Synthesis in Atrophied Soleus Muscles. European Journal of Applied Physiology. 2011. 111, 1815-1828.
3: Borgenvik, M., Nordin, M., et al. Alterations in Amino Acid Concentrations in the Plasma and Muscle in Human Subjects during 24 Hour of Simulated Adventure Racing. European Journal of Applied Physiology. 2012. Published Ahead of Print.
4: a Luz, Claudia, Nicastro, H., et al. Potential Therapeutic Effects of BCAA Supplementation on Resistance Exercise-Based Muscle Damage in Humans. Journal of the International Society of Sports Nutrition. 2011. 8(23).
5: Dualano, A, et al. Branched-Chain Amino Acids Supplementation Enhances Exercise Capacity and Lipid Oxidation During Endurance Exercise After Muscle Glycogen Depletion. Journal of Sports Medicine and Physical Fitness. 2011.51(5), 82-88.
6: Hsu, M., Chien, K., et al. Effects of BCAA, Arginine, and Carbohydrate Combined Drink on Post-Exercise Biochemical Response and Psychological Condition. Chinese Journal of Physiology. April 2011. 542), 71- 78.
7: Glynn, E., Fry, C., Drummond, M., Timmerman, K., Dhanani, S., Volpi, E., Rasmussen, B. Excess Leucine Intake Enhances Muscle Anabolic Signaling but Not Net Protein Anabolism in Young Men and Women. The Journal of Nutrition. 2010. 140(11), 1970-1976.
8: Sharp, C., Pearson, D. Amino Acid Supplements and Recovery from High-Intensity Resistance Training. Journal of Strength and Conditioning Research. 2010. 24(4), 1125-1130.
9: Ipoglou, T., King, R., Polman, R., Zanker, C. Daily L-Leucine Supplementation in Novice Trainees During a 12-Week Weight Training Program. International Journal of Sports Physiology and Performance. 2011. 6(1), 38-80.
10: Jourdan, C., et al. Body Fat Free Mass is Associated with the Serum Metabolite Profile in A Population Based Study. PLOS One. 2012. 7(6), e40009.
Imagine if you could be satisfied and content with your purchase. That can very much be your reality with the Core Nutritionals : ABC.
Inventory Last Updated: Aug 03, 2020
Carnage: Carb Complex
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The body requires a tremendous amount of energy during a rigorous weight training session and also needs the strength to recover, restore, and rebuild after a thorough workout session. The body produces this energy through the metabolism of the dietary intake throughout the day. The body nutrients are primarily comprised of Proteins, Fats, and Carbohydrates. These macronutrients are synthesized during metabolism to generate the energy required by the body to build new muscle tissues, repair and retain the old ones. They are also responsible for the energy levels during the weight training sessions. Anyone who is into progressive severe weight training will agree that the energy levels during and after workout determine the effectiveness of the workout sessions. A course that drains the energy entirely might result in cutting down on the workout session, which might cause fatigue and burn those hard-earned muscles instead of building them.
Carbohydrates are the natural energy source of the body. The body in the absence of Carbs burns the Protein, which might be harmful during the long run, as in lack of excess Protein to consume during and after a workout session, the body will end up burning the muscles, which will prove costly. Thus, to be safe, the right amount of Carbs can be added as pre, post, and even during the workout sessions. This will ensure that the muscle retains Protein, and the body gets supplied with its preferred choice of energy source.
Homopolysaccharide derived from potato, rice, and corn: It is a complex Carbohydrate consisting of identical monomers. It is the most abundant form of Carbohydrate complex that provides the body with a constant energy supply for a sustained period. It is easily absorbed by the body and ensures instant production of energy by breaking down into Glycogen during metabolism. Carbohydrates being the natural preferred energy source of the body is instantly utilized by the body while strenuous physical activity to generate energy. The natural absorption and assimilation of Homopolysaccharide derived from potato, rice, and corn ensure that it can be used as an energy source. Due to the complex structure of the Carb, the typical spike and fall of energy levels that affect the blood components are absent, making it ideal to be used as a high-performance supplement. It ensures a longer duration of the weight training sessions and faster recovery without fatigue.
It also contains artificial flavors, artificial color (red 40, yellow 6), and Sucralose.
Q. Can it be used as a pre-workout supplement?
A. It is a great pre-workout supplement and can also be used as a post-workout supplement for fast recovery.
Q: Can it be stacked with other supplements?
Q: How to use it?
A: A single scoop can be used with 8-10 oz of water, half an hour before or after training sessions.
1. Philip E Apong. Nutrition and Dietary Recommendations for Bodybuilders. Nutrition and enhanced sports performance, 737-750, 2019
2. Eric R Helms, Alan A Aragon, Peter J Fitschen. Evidence-based recommendations for natural bodybuilding contest preparation: nutrition and supplementation. Journal of the international society of sports nutrition 11 (1), 20, 2014
3. Melinda M Manore, Janice Thompson, Marcy Russo. Diet and exercise strategies of a world-class bodybuilder. International Journal of Sports Nutrition and Exercise Metabolism 3 (1), 76-86, 1993
4. Suzanne Nelson Steen. Precontest strategies of a male bodybuilder. International Journal of Sports Nutrition and Exercise Metabolism 1 (1), 69-78, 1991
5.Laura J Morrison, Frances Gizis, Barbara Shorter. Prevalent use of dietary supplements among people who exercise at a commercial gym. International journal of sports nutrition and exercise metabolism 14 (4), 481-492, 2004
6. Susan M Kleiner, Terry L Bazzarre, Barbara E Ainsworth. Nutritional status of nationally ranked elite bodybuilders. International Journal of Sports Nutrition and Exercise Metabolism 4 (1), 54-69, 1994
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The weight training session requires the body to produce enormous amounts of energy to power the workout sessions. ATP or Adenosine Triphosphate is the primary energy molecule that generates the energy needed by the body during the workout session. The production of ATP molecules in the body is facilitated by amino acid Creatine that is produced in the body by the liver, kidney, and lungs. Creatine is stored in the skeletal muscles in the form of Phosphocreatine. The body, in spite of needing vast amounts of ATP for the generation of energy, can only store ATP enough for eight seconds of a vigorous resistance training session. The production of ATP also requires that the body absorbs the Protein source and synthesize it effectively, which is achieved by the presence of water and HCL present in the body and stomach, respectively. Therefore, the supply of Creatine to the body through the dietary intake on a soluble form ensures that the body absorbs the Protein and synthesize it for energy generation instantly.
To ensure that the body is supplied with ample amounts of Creatine to boost the energy levels, and easily soluble Creatine supplement can be a wise choice.
Creatine Ethyl Ester Hcl: Creatine bonded with an Easter group and Hydrochloride. Enables fast absorption of Creatine in the body, including the fatty acid molecules. The more the amount of Creatine stored in the body, the more the energy levels.
Creatine Malate: Creatine monohydrate combined with Malic acid improves the solubility of Creatine. As a result, it is absorbed quickly. It also enhances the rate of ATP molecule generation.
Creatine HCL: Ensures fast absorption in the stomach, generates energy by forming phosphate bonds. Creatine is the natural body energy source.
Creatine Pyruvate: Creatine bonded with Pyruvic acid enables uniform levels of ATP generation during metabolism. It ensures that energy levels are at a constant high throughout the weight training session.
Creatine Nitrate: Creatine bonded with molecules of Nitric oxide. It enables the current generation of ATP molecules to negate the harmful effects of oxidation. It fights muscle fatigue and builds endurance.
Creatine Citrate: Creatine bonded with other water-soluble molecules, to enable faster and effective absorption of Creatine in the body.
Creatine Anhydrous: Creatine without any water molecule. It is pure Creatine for fast absorption, storage, and energy generation.
Creatine Orotate: Creatine bonded with Orotic acid. It ensures the process of ATP generation is efficient in the cell and helps to utilize the ATP molecules generated to the maximum. Ensuring high energy levels.
Creatine Gluconate: Creatine bonded with Glucose molecule for transportation of Creatine in the bloodstream and into the muscles. It enables effective assimilation, synthesis, and ATP production. It improves brain function and keeps the cell hydrated.
Micronized Creatine Monohydrate: The Creatine molecules are further broken down to enable faster absorption and smooth metabolism. It also ensures the purity of Creatine is the highest.
Q: Is it a pre-workout or a post-workout supplement?
A: It is a pre-workout supplement.
Q: How to use it?
A: A single scoop can be used with 8-10 oz of water, half an hour before or after training sessions.
Q. Can it be stacked with other supplements?
1. Becque, M.D. et al., 2000. Effects of oral creatine supplementation on muscular strength and body composition. Medicine and Science in Sports and Exercise
2. Ingwal JS, Weiner CD, Morales MF, Davis E, Stockdale FE: Specificity of creatine in the control of muscle protein synthesis. J Cell Biol, 1974.
3. Racette SB. Creatine supplementation and athletic performance. J Orthop Sports PhysTher. 2003
4. Kambiz KW, Pizzedaz SK. Short-term creatine supplementation improves maximum quadriceps contraction in women. Int J Sport NutrExercMetab. 2003.
5. Rawson ES, Volek JS. Effects of creatine supplementation and resistance training on muscle strength and weightlifting performance. J Strength Cond Res. 2003.
6. Kreider, R.B., 1999. Dietary supplements and the promotion of muscle growth with resistance exercise. Sports Medicine
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